Dennis L. Kasper MD, MA(HON)William Ellery Channing Professor of Medicine, Professor of Microbiology and Molecular Genetics, Harvard Medical School; Director, Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Boston, MassachusettsAnthony S. Fauci, MD Sc(HON)Chief Laboratory of Immunoregulation: Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MarylandStephen L. Hauser, MDRobert A. Fishman, Distinguished Professor and Chairman, Department of Neurology, University of California ,San Francisco, San Francisco, CaliforniaDan L. Longo, MDProfessor of Medicine, Harvard Medical School; Senior Physician, Brigham and Women’s Hospital; Deputy Editor, New England Journal of Medicine, Boston, Massachusetts; Adjunct Investigator, National Institute on Aging, National Institutes of Health, Bethesda, MarylandJ. Larry Jameson, MD, PhDRobert G. Dunlop Professor of Medicine; Dean, University of Pennsylvania Perelman School of Medicine, Executive Vice-President, University of Pennsylvania Health System, Philadelphia, PennsylvaniaJoseph Loscalzo, MD, PhDHersey Professor of the Theory and Practice of Medicine, Harvard Medical School; Chairman, Department of Medicine; Physician-in-Chief, Brigham and Woman’s Hospital, Boston, Massachusetts